BACKGROUND: Diabetic neuroosteoarthropathy (DNOAP, Charcot’s foot) - is a progressive destructive inflammatory disease of the osteoarticular apparatus of the foot, untimely and inadequate treatment of which can lead to the formation of gross deformities.More often, DNOAP is unilateral, bilateral lesion is relatively rare.It is not always poss
Development of an Automated MRI-Based Diagnostic Protocol for Amyotrophic Lateral Sclerosis Using Disease-Specific Pathognomonic Features: A Quantitative Disease-State Classification Study.
Despite significant diablo 2 amn advances in quantitative neuroimaging, the diagnosis of ALS remains clinical and MRI-based biomarkers are not currently used to aid the diagnosis.The objective of this study is to develop a robust, disease-specific, multimodal classification protocol and validate its diagnostic accuracy in independent, early-stage a
Autonomic regulation of brown adipose tissue thermogenesis in health & disease: Potential clinical applications for altering BAT thermogenesis
From mouse to man, brown adipose tissue (BAT) is a significant source of thermogenesis contributing to the maintenance of the body temperature homeostasis during the challenge of low environmental temperature.In rodents, BAT thermogenesis also contributes to the febrile increase in core temperature during the immune response.BAT sympathetic nerve a